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Novel active substances needed – more than ever

A crucial point about infections is the fact that a drug’s activity ebbs from the very beginning of its market entrance. According to the cause-and-effect chain, the microbes learn to develop new defense strategies with each contact to the drug. The resistant genes are transferred from one germ to another, the genome reconstructs and, step by step, the microbes become resistant.

According to the CDC (Center for Disease Control and Prevention), a high proportion of nosocomial infections have become resistant against common antibiotics. A majority of effective drugs used in the past have totally lost their activity.