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Infections – holding humankind hostage

Today, infectious diseases are one of the leading causes of death worldwide and a substantial health threat.

The number of effective therapeutic measures against serious life-threatening infections has fallen dramatically because of multi-drug resistance of the invasive pathogens.

Especially for children, the aged and immune-suppressed patients, the situation is extremely threatening. Infections with multi-drug resistant microbes in hospitals (nosocomial infections) have become increasingly common, with about 9 million cases worldwide and a mortality rate of around 4.5%. The follow-up costs for therapies are enormous because most of the infections appear at intensive care or post-operative activities and distinctly prolong hospitalization.
Unfortunately, this issue goes beyond the hospital environment. In the past years, numerous disease outbreaks have appeared after hospitalization; resistant pathogens were transferred as stowaways to a broader population. Combined with today’s increasing mobility, this has spread dangerous pathogens worldwide. A case in point is the avian flu several years ago or the current swine influenza.